BDBM531036 (S)-4-(4-(1H-imidazol-4-yl)piperidin-1-yl)-N1-(2,3-diaminopropyl)-3-(2H-tetrazol-5-yl)benzene-1,2-disulfonamide::US11207312, Example 168

SMILES NC[C@H](N)CNS(=O)(=O)c1ccc(N2CCC(CC2)c2c[nH]cn2)c(-c2nn[nH]n2)c1S(N)(=O)=O

InChI Key InChIKey=OULGJNXHRCRUSI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 531036   

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM531036(US11207312, Example 168 | (S)-4-(4-(1H-imidazol-4-...)
Affinity DataIC50: 0.170nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-lactamase(Pseudomonas aeruginosa)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM531036(US11207312, Example 168 | (S)-4-(4-(1H-imidazol-4-...)
Affinity DataIC50: 0.240nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVIM-1 metallo-beta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM531036(US11207312, Example 168 | (S)-4-(4-(1H-imidazol-4-...)
Affinity DataIC50: 0.0700nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM531036(US11207312, Example 168 | (S)-4-(4-(1H-imidazol-4-...)
Affinity DataIC50: 0.480nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails
US Patent