BDBM529976 (3R)-4-(3,3- difluoro-2,2- dimethyl- propanoyl)-3- methyl-3,5-dihydro- 2H-pyrido[3,4- f][1,4]oxazepine-9- carbonitrile::US11203600, Example 52

SMILES C[C@@H]1COc2c(CN1C(=O)C(C)(C)C(F)F)cncc2C#N

InChI Key InChIKey=BASCLMORXIDBHI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529976   

TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM529976((3R)-4-(3,3- difluoro-2,2- dimethyl- propanoyl)-3-...)
Affinity DataIC50: 100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
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US Patent