BDBM529971 4-(4,4,4-trifluoro- 2,2-dimethyl- butanoyl)-3,5- dihydro-2H- pyrido[3,4- f][1,4]oxazepine-9- carbonitrile::US11203600, Example 47

SMILES CC(C)(CC(F)(F)F)C(=O)N1CCOc2c(C1)cncc2C#N

InChI Key InChIKey=UHFXWGQAHILKEQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529971   

TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM529971(4-(4,4,4-trifluoro- 2,2-dimethyl- butanoyl)-3,5- d...)
Affinity DataIC50: 100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
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US Patent