BDBM529944 3,3-difluoro-1-(6- fluoro-2,3- dihydrobenzo[f] [1,4]oxazepin- 4(5H)-yl)-2,2- dimethylpropan-1- one::US11203600, Example 20

SMILES CC(C)(C(F)F)C(=O)N1CCOc2cccc(F)c2C1

InChI Key InChIKey=HSMBKTKGVITQIM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529944   

TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM529944(3,3-difluoro-1-(6- fluoro-2,3- dihydrobenzo[f] [1,...)
Affinity DataIC50: 100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
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US Patent