BDBM528529 US11192850, Entry 4a

SMILES COC(=O)c1ccc(cc1)C#Cc1ccc(NC(=O)C(O)=O)cc1

InChI Key InChIKey=JMZYPZQWJABIMF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 528529   

TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Purdue Research Foundation

US Patent
LigandPNGBDBM528529(US11192850, Entry 4a)
Affinity DataIC50: 23nMAssay Description:Compounds were tested against mPTPB using the p-nitrophenyl phosphate (pNPP) assay system in a Cary 100 UV-Vis spectrophotometer by monitoring the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM528529(US11192850, Entry 4a)
Affinity DataIC50: 5.26E+4nMAssay Description:Compounds were tested against mPTPB using the p-nitrophenyl phosphate (pNPP) assay system in a Cary 100 UV-Vis spectrophotometer by monitoring the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM528529(US11192850, Entry 4a)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds were tested against mPTPB using the p-nitrophenyl phosphate (pNPP) assay system in a Cary 100 UV-Vis spectrophotometer by monitoring the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM528529(US11192850, Entry 4a)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds were tested against mPTPB using the p-nitrophenyl phosphate (pNPP) assay system in a Cary 100 UV-Vis spectrophotometer by monitoring the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
Go to US Patent