BDBM526501 US11186566, Compound 40
SMILES C[C@@H]1CN(c2nc(ccc2C(=O)NS(=O)(=O)c2ccccc2)-n2ccc(OCC3C[C@@H]4CC[C@@H]3C4)n2)C(C)(C)C1
InChI Key
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 526501
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Human)
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataEC50: <100nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Human)
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataEC50: 80nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair