BDBM525848 US11174254, Compound G-9

SMILES CC(C)(O)Cn1cc(Nc2nc(Nc3cccc(NC(=O)C=C)c3)nc3CNC(=O)c23)cn1

InChI Key InChIKey=BQYKZLKROGIWLI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 525848   

TargetTyrosine-protein kinase BTK(Human)
Yangtze River Pharmaceutical Group

US Patent
LigandPNGBDBM525848(US11174254, Compound G-9)
Affinity DataIC50: 55nMAssay Description:The compound was predissolved in 100% DMSO.10 mM drug stock solution was obtained by dissolution at room temperature and then gradiently diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
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TargetEpidermal growth factor receptor(Human)
Yangtze River Pharmaceutical Group

US Patent
LigandPNGBDBM525848(US11174254, Compound G-9)
Affinity DataIC50: 5.03E+3nMAssay Description:The inhibitory activity of compounds to be tested on wild-type EGFR kinase (Invitrogen, PV3872) was measured by z-lyte methods.The working concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent