BDBM524884 US11168102, Example 1-8.

SMILES C[C@@H](Nc1ncnc2n(C)c(=O)c(cc12)C1=CCN(C)CC1)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=VFECQHRUUIFSHG-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 524884   

TargetSon of sevenless homolog 1 [564-1049]()
Revolution Medicines

US Patent
LigandPNGBDBM524884(US11168102, Example 1-8.)
Affinity DataKd:  20nMAssay Description:The purpose of this assay was to characterize the inhibitory activity of compounds on SOS1 nucleotide exchange of KRAS. Data was reported as IC50 val...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSon of sevenless homolog 1 [564-1049]()
Revolution Medicines

US Patent
LigandPNGBDBM524884(US11168102, Example 1-8.)
Affinity DataIC50: 20.1nMAssay Description:Using a GE Biacore 8K SPR instrument, avi-tagged SOS1 catalytic domain protein was immobilized to a level of approximately 6000 response units (RU) o...More data for this Ligand-Target Pair
In DepthDetails
US Patent