BDBM524879 US11168095, Example 19

SMILES C=Cc1ccc2OCCCCn3cnnc3-c3cccc(NC(=O)c2c1)n3

InChI Key InChIKey=AUJMXOPTGQDCIO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 524879   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM524879(US11168095, Example 19)
Affinity DataIC50: 100nMAssay Description:Table 1: Briefly, 20 μL aliquots of a 1.5× stock of ASK1, STK Substrate 3 and Assay Buffer were distributed in the wells of a white 384 well Opt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent