BDBM524519 Preparation of 1-isopropyl-3-(methoxymethyl)-N-(5-(piperazin-1-yl)pyridin-2-yl)-4,5-dihydro-1H-pyrazolo[4,3-H]quinazolin-8-amine ::US11168088, Compound P-59

SMILES COCc1nn(C(C)C)c-2c1CCc1cnc(Nc3ccc(cn3)N3CCNCC3)nc-21

InChI Key InChIKey=ZQQINGGAGOJSFQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 524519   

LigandPNGBDBM524519(US11168088, Compound P-59 | Preparation of 1-isopr...)
Affinity DataIC50: 21nMAssay Description:In the kinase test, a compound to be tested was 1:3 diluted for 8 gradient points, added into a reaction plate, and then added an appropriate amount ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
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LigandPNGBDBM524519(US11168088, Compound P-59 | Preparation of 1-isopr...)
Affinity DataIC50: 83nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
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LigandPNGBDBM524519(US11168088, Compound P-59 | Preparation of 1-isopr...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
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TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
TBA

US Patent
LigandPNGBDBM524519(US11168088, Compound P-59 | Preparation of 1-isopr...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent