BDBM524491 Preparation of 9-isopropyl-N-(5-(piperazin-1-yl)pyridin-2-yl)-6,8-dihydro-5H-pyrazolo[3,4-H]quinazolin-2-amine ::US11168088, Compound P-29

SMILES CC(C)c1[nH]nc2CCc3cnc(Nc4ccc(cn4)N4CCNCC4)nc3-c12

InChI Key InChIKey=LVDUGVRJAIDNFO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 524491   

LigandPNGBDBM524491(US11168088, Compound P-29 | Preparation of 9-isopr...)
Affinity DataIC50: 7nMAssay Description:In the kinase test, a compound to be tested was 1:3 diluted for 8 gradient points, added into a reaction plate, and then added an appropriate amount ...More data for this Ligand-Target Pair
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Date in BDB:
3/27/2022
Entry Details
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LigandPNGBDBM524491(US11168088, Compound P-29 | Preparation of 9-isopr...)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
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LigandPNGBDBM524491(US11168088, Compound P-29 | Preparation of 9-isopr...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
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TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
TBA

US Patent
LigandPNGBDBM524491(US11168088, Compound P-29 | Preparation of 9-isopr...)
Affinity DataIC50: 457nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent