BDBM524477 Preparation of N-(5-(4-methylpiperazin-1-yl)pyridin-2-yl)-1-isopropyl-4,5-dihydro-1H-pyrazolo[4,3H]quinazolin-8-amine ::US11168088, Compound P-12

SMILES CCN1CCN(CC1)c1ccc(Nc2ncc3CCc4cnn(C(C)C)c4-c3n2)nc1

InChI Key InChIKey=MNRQIMCIRPOLBI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 524477   

LigandPNGBDBM524477(US11168088, Compound P-12 | Preparation of N-(5-(4...)
Affinity DataIC50: 8nMAssay Description:In the kinase test, a compound to be tested was 1:3 diluted for 8 gradient points, added into a reaction plate, and then added an appropriate amount ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
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LigandPNGBDBM524477(US11168088, Compound P-12 | Preparation of N-(5-(4...)
Affinity DataIC50: 36nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
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LigandPNGBDBM524477(US11168088, Compound P-12 | Preparation of N-(5-(4...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
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TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
TBA

US Patent
LigandPNGBDBM524477(US11168088, Compound P-12 | Preparation of N-(5-(4...)
Affinity DataIC50: 7.98E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent