BDBM524468 Preparation of 8-ethyl-N-(5-((4-methylpiperazin-1-yl)methyl)pyridin-2-yl)-9-isopropyl-6,8-dihydro-5H-pyrazolo[3,4-H]quinolin-2-amine ::US11168088, Compound P-2

SMILES CCN1CCN(Cc2ccc(Nc3ncc4CCc5nn(CC)c(C(C)C)c5-c4n3)nc2)CC1

InChI Key InChIKey=DXQYRMHOIONXFX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 524468   

LigandPNGBDBM524468(US11168088, Compound P-2 | Preparation of 8-ethyl-...)
Affinity DataIC50: 4nMAssay Description:In the kinase test, a compound to be tested was 1:3 diluted for 8 gradient points, added into a reaction plate, and then added an appropriate amount ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
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LigandPNGBDBM524468(US11168088, Compound P-2 | Preparation of 8-ethyl-...)
Affinity DataIC50: 38nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
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LigandPNGBDBM524468(US11168088, Compound P-2 | Preparation of 8-ethyl-...)
Affinity DataIC50: 427nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
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TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
TBA

US Patent
LigandPNGBDBM524468(US11168088, Compound P-2 | Preparation of 8-ethyl-...)
Affinity DataIC50: 896nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent