BDBM523898 6-(4-Cyclopropyl-1H-imidazol-1-yl)-2-(6-(6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-3-yl)pyridin-2-yl)-5-methylisoindolin-1-one::US11136324, Example 63
SMILES Cc1cc2CN(C(=O)c2cc1-n1cnc(c1)C1CC1)c1cccc(n1)-c1nnc2CCCn12
InChI Key InChIKey=HWHNEHGSAFMHDU-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 523898
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group
US Patent
Jiangsu Hansoh Pharmaceutical Group
US Patent
Affinity DataIC50: 8.40nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair