BDBM523897 N-(6-(6′,7′-Dihydrospiro[cyclopropane-1,5′-pyrrolo[2,1-c][1,2,4]triazol]-3′-yl)pyridin-2-yl)-2-fluoro-5-(4-isopropyl-1H-imidazol-1-yl)-4-methylbenzamide::US11136324, Example 62

SMILES CC(C)c1cn(cn1)-c1cc(C(=O)Nc2cccc(n2)-c2nnc3CCC4(CC4)n23)c(F)cc1C

InChI Key InChIKey=SHBDCIKKQVCTNP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 523897   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM523897(US11136324, Example 62 | N-(6-(6′,7′-D...)
Affinity DataIC50: 3nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
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Date in BDB:
3/27/2022
Entry Details
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