BDBM523873 (S)-2-Fluoro-5-(4-isopropyl-1H-imidazol-1-yl)-4-methyl-N-(6-(5-methyl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-3-yl)pyridin-2-yl)benzamide::US11136324, Example 14

SMILES CC(C)c1cn(cn1)-c1cc(C(=O)Nc2cccc(n2)-c2nnc3CC[C@H](C)n23)c(F)cc1C

InChI Key InChIKey=YDBRVFWQGCMUTC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 523873   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM523873(US11136324, Example 14 | (S)-2-Fluoro-5-(4-isoprop...)
Affinity DataIC50: 9nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
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