BDBM521876 US11155546, Compound G-59

SMILES Cn1cc(Nc2nc(NC3CCCN(C3)C(=O)C=C)nc3CNC(=O)c23)cn1

InChI Key InChIKey=HGGGFNLVPKEMAV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 521876   

TargetTyrosine-protein kinase BTK(Human)
Shanghai Haiyan Pharmaceutical Technology

US Patent
LigandPNGBDBM521876(US11155546, Compound G-59)
Affinity DataIC50: 13nMAssay Description:BTK: The compound was predissolved in 100% DMSO. 10 mM drug stock solution was obtained by dissolution at room temperature and then serially diluted ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Haiyan Pharmaceutical Technology

US Patent
LigandPNGBDBM521876(US11155546, Compound G-59)
Affinity DataIC50: 1.02E+3nMAssay Description:EGFR: The working concentration of each component in 10 μl wild-type EGFR kinase reaction system was: 10 μM ATP, 0.8 ng/μl wild-type E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent