BDBM52057 (2,5-Dimethoxy-phenyl)-(5-hydroxy-4-morpholin-4-ylmethyl-benzofuran-3-yl)-methanone::(2,5-dimethoxyphenyl)-[4-(morpholin-4-ylmethyl)-5-oxidanyl-1-benzofuran-3-yl]methanone::(2,5-dimethoxyphenyl)-[5-hydroxy-4-(4-morpholinylmethyl)-3-benzofuranyl]methanone::(2,5-dimethoxyphenyl)-[5-hydroxy-4-(morpholin-4-ylmethyl)-1-benzofuran-3-yl]methanone::(2,5-dimethoxyphenyl)-[5-hydroxy-4-(morpholinomethyl)benzofuran-3-yl]methanone::CHEMBL1393757::MLS000075556::SMR000010588::cid_645092

SMILES COc1ccc(OC)c(c1)C(=O)c1coc2ccc(O)c(CN3CCOCC3)c12

InChI Key InChIKey=HEFRYOSFVSUCDR-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 52057   

TargetPOsterior Segregation(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM52057((2,5-Dimethoxy-phenyl)-(5-hydroxy-4-morpholin-4-yl...)
Affinity DataEC50:  3.00E+5nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay
TargetZinc finger protein mex-5(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM52057((2,5-Dimethoxy-phenyl)-(5-hydroxy-4-morpholin-4-yl...)
Affinity DataEC50:  3.00E+5nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM52057((2,5-Dimethoxy-phenyl)-(5-hydroxy-4-morpholin-4-yl...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged SIRT1 coding region (156-664) (unknown origin) expressed in Escherichia coli BL21(DE3) using 31.25 uM ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed