BDBM520005 (R)-methyl 4-(2-chloro-4-fluorophenyl)-6-(((S)-2-(3-(4-(hydroxymethyl)phenyl) prop-2-yn-1-yl)-3-oxohexahydroimidazo[1,5-a]pyrazin-7(1H)-yl)methyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate::US11142527, Example 37

SMILES COC(=O)C1=C(CN2CCN3[C@H](CN(CC#Cc4ccc(CO)cc4)C3=O)C2)NC(=N[C@H]1c1ccc(F)cc1Cl)c1nccs1

InChI Key InChIKey=YSUZPSONSHVGRM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 520005   

TargetLarge envelope protein(HBV-D)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM520005((R)-methyl 4-(2-chloro-4-fluorophenyl)-6-(((S)-2-(...)
Affinity DataEC50:  12.1nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
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