BDBM518854 US11117865, Compound ZL0497

SMILES FC(F)(F)c1ccc(NC(=O)Nc2ccc(cc2)S(=O)(=O)N2CCCC2)cc1

InChI Key InChIKey=DSKPBLLDJJBUMD-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 518854   

TargetBromodomain-containing protein 4 [49-170](Human)
University Of Texas

US Patent
LigandPNGBDBM518854(US11117865, Compound ZL0497)
Affinity DataIC50: 1.00E+4nMAssay Description:Determine the binding ability of BRD4 compounds to bromodomains of BRD2 and BRD4. 96 well plate based commercial TR-FRET Assay kits (Cayman Chemical,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
University Of Texas

US Patent
LigandPNGBDBM518854(US11117865, Compound ZL0497)
Affinity DataIC50: 1.00E+4nMAssay Description:Determine the binding ability of BRD4 compounds to bromodomains of BRD2 and BRD4. 96 well plate based commercial TR-FRET Assay kits (Cayman Chemical,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 2 [91-163](Human)
University Of Texas

US Patent
LigandPNGBDBM518854(US11117865, Compound ZL0497)
Affinity DataIC50: 1.00E+4nMAssay Description:Determine the binding ability of BRD4 compounds to bromodomains of BRD2 and BRD4. 96 well plate based commercial TR-FRET Assay kits (Cayman Chemical,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 2 [364-436](Human)
University Of Texas

US Patent
LigandPNGBDBM518854(US11117865, Compound ZL0497)
Affinity DataIC50: 1.00E+4nMAssay Description:Determine the binding ability of BRD4 compounds to bromodomains of BRD2 and BRD4. 96 well plate based commercial TR-FRET Assay kits (Cayman Chemical,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University Of Texas

US Patent
LigandPNGBDBM518854(US11117865, Compound ZL0497)
Affinity DataIC50: 1.00E+4nMAssay Description:Determine the binding ability of BRD4 compounds to bromodomains of BRD2 and BRD4. 96 well plate based commercial TR-FRET Assay kits (Cayman Chemical,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 3 [326-398](Human)
University Of Texas

US Patent
LigandPNGBDBM518854(US11117865, Compound ZL0497)
Affinity DataIC50: 1.00E+4nMAssay Description:Determine the binding ability of BRD4 compounds to bromodomains of BRD2 and BRD4. 96 well plate based commercial TR-FRET Assay kits (Cayman Chemical,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2022
Entry Details
Go to US Patent

TargetBromodomain testis-specific protein [22-138](Human)
University Of Texas

US Patent
LigandPNGBDBM518854(US11117865, Compound ZL0497)
Affinity DataIC50: 1.00E+4nMAssay Description:Determine the binding ability of BRD4 compounds to bromodomains of BRD2 and BRD4. 96 well plate based commercial TR-FRET Assay kits (Cayman Chemical,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2022
Entry Details
Go to US Patent

TargetBromodomain testis-specific protein [287-359](Human)
University Of Texas

US Patent
LigandPNGBDBM518854(US11117865, Compound ZL0497)
Affinity DataIC50: 1.00E+4nMAssay Description:Determine the binding ability of BRD4 compounds to bromodomains of BRD2 and BRD4. 96 well plate based commercial TR-FRET Assay kits (Cayman Chemical,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2022
Entry Details
Go to US Patent

TargetCREB-binding protein(Human)
University Of Texas

US Patent
LigandPNGBDBM518854(US11117865, Compound ZL0497)
Affinity DataIC50: 1.00E+4nMAssay Description:Determine the binding ability of BRD4 compounds to bromodomains of BRD2 and BRD4. 96 well plate based commercial TR-FRET Assay kits (Cayman Chemical,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2022
Entry Details
Go to US Patent