BDBM518432 US11124500, Example 24b

SMILES C[C@H]1CCN1c1nc(cc(c1C#N)C(F)(F)F)-c1cnn(C[C@H](O)CO)c1

InChI Key InChIKey=XVQYJNLYUFGIDG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 518432   

TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518432(US11124500, Example 24b)
Affinity DataIC50: 4.89nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518432(US11124500, Example 24b)
Affinity DataIC50: 6.75nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In DepthDetails
US Patent