BDBM517309 3-(2-chloro-5-cyanophenyl)-N- (1,1-dioxidotetrahydrothiophen- 3-yl)-1-(5-fluoropyridin-2-yl)- 1H-indazole-6-carboxamide (enantiomer A)::US11104690, Example 127-A

SMILES Fc1ccc(nc1)-n1nc(-c2cc(ccc2Cl)C#N)c2ccc(cc12)C(=O)N[C@@H]1CCS(=O)(=O)C1

InChI Key InChIKey=KQFPHJVIRRERAD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517309   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM517309(US11104690, Example 127-A | 3-(2-chloro-5-cyanophe...)
Affinity DataIC50: 8.20nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
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