BDBM517275 US11104690, Example 100::tert-butyl (3S)-3-({[3-(2- chlorophenyl)-1-(4- fluorophenyl)-1H-indazol-6- yl]carbonyl}amino)pyrrolidine-1- carboxylate

SMILES CC(C)(C)OC(=O)N1CC[C@@H](C1)NC(=O)c1ccc2c(nn(-c3ccc(F)cc3)c2c1)-c1ccccc1Cl

InChI Key InChIKey=QWUFVCIGYZDHCD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517275   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM517275(US11104690, Example 100 | tert-butyl (3S)-3-({[3-(...)
Affinity DataIC50: 12nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent