BDBM517246 3-(2-chlorophenyl)-1-(4- fluorophenyl)-N-[(1S,2R,5R)-2- hydroxy-5-methylcyclopentyl]- 1H-indazole-6-carboxamide::US11104690, Example 72

SMILES C[C@@H]1CC[C@@H](O)[C@H]1NC(=O)c1ccc2c(nn(-c3ccc(F)cc3)c2c1)-c1ccccc1Cl

InChI Key InChIKey=JWKSXTTXAYKCTH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517246   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM517246(US11104690, Example 72 | 3-(2-chlorophenyl)-1-(4- ...)
Affinity DataIC50: 22nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent