BDBM516831 US11104664, Compound P-2::US11104664, Compound P-3

SMILES CCN(C1CCOCC1)c1c(C)c(cc2[nH]ncc12)C(=O)NCc1c(OC)cc(C)[nH]c1=O

InChI Key InChIKey=UZNYUSLGURPKOF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 516831   

LigandPNGBDBM516831(US11104664, Compound P-3 | US11104664, Compound P-...)
Affinity DataIC50: 24nMAssay Description:Recombinant PRC2 (EZH2-Y641F) was purchased from Active motif, S-adenosyl-methionine (SAM) and Poly-L-lysine (PLL) were purchased from Sigma-Aldrich,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent

LigandPNGBDBM516831(US11104664, Compound P-3 | US11104664, Compound P-...)
Affinity DataIC50: 154nMAssay Description:Recombinant PRC2 (EZH2-Y641F) was purchased from Active motif, S-adenosyl-methionine (SAM) and Poly-L-lysine (PLL) were purchased from Sigma-Aldrich,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent