BDBM515773 US11053225, Compound 23

SMILES Cn1cc(cn1)-c1cnc(NC23CC4CC(CC(C4)C2)C3)nc1NC1CCCCC1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 515773   

TargetTyrosine-protein kinase receptor TYRO3(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM515773(US11053225, Compound 23)
Affinity DataIC50: 610nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
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TargetTyrosine-protein kinase receptor UFO(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM515773(US11053225, Compound 23)
Affinity DataIC50: 1.00E+4nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM515773(US11053225, Compound 23)
Affinity DataIC50: 0nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent