BDBM514783 US11098041, Example 5

SMILES Cc1c(NC(=O)c2ccc(cc2)C(C)(C)C)cccc1-c1ccnc2[nH]c(nc12)-c1ccc(cc1)C(=O)N1CCOCC1

InChI Key InChIKey=CMNOPGSZOYYDCD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 514783   

TargetTyrosine-protein kinase BTK(Human)
Merck Patent

US Patent
LigandPNGBDBM514783(US11098041, Example 5)
Affinity DataIC50: 100nMAssay Description:Briefly, 2.5× stocks of full-length human BTK (08-080) from CarnaBio USA, Inc., Natick, Mass., 1.6×ATP and appropriate kinKDR peptide substrate (FITC...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK [328-659](Human)
Merck Patent

US Patent
LigandPNGBDBM514783(US11098041, Example 5)
Affinity DataIC50: 100nMAssay Description:The protocol below describes a microfluidic, off-chip mobility shift kinase assay to measure inherent potency of compounds against BTK C481S enzyme. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase BTK(Human)
Merck Patent

US Patent
LigandPNGBDBM514783(US11098041, Example 5)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck Patent

US Patent
LigandPNGBDBM514783(US11098041, Example 5)
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed