BDBM514556 8-(7- (trifluoromethyl)imidazo[1,5- a]pyridin-5-yl)-2,8- diazaspiro[4.5]decane-1,3- dione::US11096930, Example 13

SMILES FC(F)(F)c1cc(N2CCC3(CC(=O)NC3=O)CC2)n2cncc2c1

InChI Key InChIKey=GGTOBYVWDBWTJG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 514556   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM514556(8-(7- (trifluoromethyl)imidazo[1,5- a]pyridin-5-yl...)
Affinity DataIC50: 295nMAssay Description:Recombinant human IDO or TDO was incubated in 50 mM KPO4 (pH 7.0), 0.5 mM EGTA, 0.5 mM EDTA, 0.05% Triton X100, 20 mM ascorbate, 10 μM methylene...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM514556(8-(7- (trifluoromethyl)imidazo[1,5- a]pyridin-5-yl...)
Affinity DataIC50: 1.70E+3nMAssay Description:Recombinant human IDO or TDO was incubated in 50 mM KPO4 (pH 7.0), 0.5 mM EGTA, 0.5 mM EDTA, 0.05% Triton X100, 20 mM ascorbate, 10 μM methylene...More data for this Ligand-Target Pair
In DepthDetails
US Patent