BDBM514540 US11096924, DASH-inhibitors 5320::US11583516, Cmpd ID 5320

SMILES CC1(CCCCC1)[C@H](N)C(=O)N1Cc2ccc(F)cc2C1

InChI Key InChIKey=HTMJAHPTKGPGQR-UHFFFAOYSA-N

Data  21 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 514540   

TargetDipeptidyl peptidase 2(Human)
Tufts College

US Patent
LigandPNGBDBM514540(US11096924, DASH-inhibitors 5320 | US11583516, Cmp...)
Affinity DataIC50: 5.39E+4nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 8/9(Human)
Tufts College

US Patent
LigandPNGBDBM514540(US11096924, DASH-inhibitors 5320 | US11583516, Cmp...)
Affinity DataIC50: 280nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetPresequence protease, mitochondrial (PREP)(Human)
Tufts College

US Patent
LigandPNGBDBM514540(US11096924, DASH-inhibitors 5320 | US11583516, Cmp...)
Affinity DataIC50: 8.95E+4nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM514540(US11096924, DASH-inhibitors 5320 | US11583516, Cmp...)
Affinity DataIC50: 1.00E+5nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 2(Human)
Tufts College

US Patent
LigandPNGBDBM514540(US11096924, DASH-inhibitors 5320 | US11583516, Cmp...)
Affinity DataIC50: 5.39E+4nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Tufts College

US Patent
LigandPNGBDBM514540(US11096924, DASH-inhibitors 5320 | US11583516, Cmp...)
Affinity DataIC50: 2.07E+3nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 9(Human)
Tufts College

US Patent
LigandPNGBDBM514540(US11096924, DASH-inhibitors 5320 | US11583516, Cmp...)
Affinity DataIC50: 7.90nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 8(Human)
Tufts College

US Patent
LigandPNGBDBM514540(US11096924, DASH-inhibitors 5320 | US11583516, Cmp...)
Affinity DataIC50: 1.90nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 8/9(Human)
Tufts College

US Patent
LigandPNGBDBM514540(US11096924, DASH-inhibitors 5320 | US11583516, Cmp...)
Affinity DataIC50: 280nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetProlyl endopeptidase(Human)
Tufts College

US Patent
LigandPNGBDBM514540(US11096924, DASH-inhibitors 5320 | US11583516, Cmp...)
Affinity DataIC50: 8.95E+4nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM514540(US11096924, DASH-inhibitors 5320 | US11583516, Cmp...)
Affinity DataIC50: 1.00E+5nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 8(Human)
Tufts College

US Patent
LigandPNGBDBM514540(US11096924, DASH-inhibitors 5320 | US11583516, Cmp...)
Affinity DataIC50: 1.90E+3nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Tufts College

US Patent
LigandPNGBDBM514540(US11096924, DASH-inhibitors 5320 | US11583516, Cmp...)
Affinity DataIC50: 2.07E+3nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 9(Human)
Tufts College

US Patent
LigandPNGBDBM514540(US11096924, DASH-inhibitors 5320 | US11583516, Cmp...)
Affinity DataIC50: 7.90nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 8(Human)
Tufts College

US Patent
LigandPNGBDBM514540(US11096924, DASH-inhibitors 5320 | US11583516, Cmp...)
Affinity DataIC50: 1.90nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 8/9(Human)
Tufts College

US Patent
LigandPNGBDBM514540(US11096924, DASH-inhibitors 5320 | US11583516, Cmp...)
Affinity DataIC50: 2.80E+5nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetHomeobox protein PKNOX1(Human)
Tufts College

US Patent
LigandPNGBDBM514540(US11096924, DASH-inhibitors 5320 | US11583516, Cmp...)
Affinity DataIC50: 8.95E+7nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM514540(US11096924, DASH-inhibitors 5320 | US11583516, Cmp...)
Affinity DataIC50: 1.00E+8nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 2(Human)
Tufts College

US Patent
LigandPNGBDBM514540(US11096924, DASH-inhibitors 5320 | US11583516, Cmp...)
Affinity DataIC50: 5.39E+7nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Tufts College

US Patent
LigandPNGBDBM514540(US11096924, DASH-inhibitors 5320 | US11583516, Cmp...)
Affinity DataIC50: 2.07E+6nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 9(Human)
Tufts College

US Patent
LigandPNGBDBM514540(US11096924, DASH-inhibitors 5320 | US11583516, Cmp...)
Affinity DataIC50: 7.90E+3nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent