BDBM514521 US11096924, DASH-inhibitors 4268::US11583516, Cmpd ID 4268

SMILES CC(C)(F)[C@H](N)C(=O)N1CCC[C@H]1B(O)O

InChI Key InChIKey=ZNNCLYSYFNMXCX-UHFFFAOYSA-N

Data  21 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 514521   

TargetDipeptidyl peptidase 2(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50: 68nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 8/9(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50: 27nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPresequence protease, mitochondrial (PREP)(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50: 23nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProlyl endopeptidase FAP(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50: 75nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 2(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50: 68nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 4(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50: 12nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50: 14nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 8(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50: 10nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 8/9(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50: 28nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProlyl endopeptidase(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50: 23nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProlyl endopeptidase FAP(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50: 75nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 8(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50: 1.00E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 4(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50: 12nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50: 14nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 8(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50: 10nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 8/9(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50: 2.80E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHomeobox protein PKNOX1(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50: 2.30E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProlyl endopeptidase FAP(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50: 7.50E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 2(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50: 6.80E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 4(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50: 1.20E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514521(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...)
Affinity DataIC50: 1.40E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In DepthDetails
US Patent