BDBM514520 US11096924, DASH-inhibitors 4175 CP::US11583516, Cmpd ID 4175CP

SMILES CC1(CCCC1)[C@H](N)C(=O)N1CCC[C@H]1B(O)O

InChI Key InChIKey=IWHLQEBGPICVMJ-UHFFFAOYSA-N

Data  21 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 514520   

TargetDipeptidyl peptidase 2(Human)
Tufts College

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 9.20nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
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TargetDipeptidyl peptidase 8/9(Human)
Tufts College

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 27nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetPresequence protease, mitochondrial (PREP)(Human)
Tufts College

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 68nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 88nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 2(Human)
Tufts College

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 9.20nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Tufts College

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 2.90nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 9(Human)
Tufts College

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 5.60nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 8(Human)
Tufts College

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 5.30nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 8/9(Human)
Tufts College

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 27nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetProlyl endopeptidase(Human)
Tufts College

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 68nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 88nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 8(Human)
Tufts College

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 5.30E+3nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Tufts College

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 2.90nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 9(Human)
Tufts College

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 5.60nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 8(Human)
Tufts College

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 5.30nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 8/9(Human)
Tufts College

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 2.70E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetHomeobox protein PKNOX1(Human)
Tufts College

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 6.80E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 8.80E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 2(Human)
Tufts College

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 9.20E+3nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Tufts College

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 2.90E+3nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 9(Human)
Tufts College

US Patent
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 5.60E+3nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent