BDBM514424 1-(((S)-1-((S)-3-Cyclobutyl-2-(hydroxymethyl)propanoyl)-4-hydroxy-3,3-dimethylpiperidin-4-yl)methyl)-N,N-dimethyl-6-oxo-4-phenyl-1,6-dihydropyridine-3-carboxamide and 1-(((R)-1-((S)-3-Cyclobutyl-2-(hydroxymethyl)propanoyl)-4-hydroxy-3,3-dimethylpiperidin-4-yl)methyl)-N,N-dimethyl-6-oxo-4-phenyl-1,6-dihydropyridine-3-carboxamide::US11053213, Example 166

SMILES CN(C)C(=O)c1cn(C[C@]2(O)CCN(CC2(C)C)C(=O)[C@H](CO)CC2CCC2)c(=O)cc1-c1ccccc1

InChI Key InChIKey=SURQKOABNLFGKI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 514424   

TargetUbiquitin carboxyl-terminal hydrolase 19(Human)
Almac Discovery

US Patent
LigandPNGBDBM514424(1-(((S)-1-((S)-3-Cyclobutyl-2-(hydroxymethyl)propa...)
Affinity DataIC50: 500nMAssay Description:USP19 activity was monitored in a fluorescence polarisation (FP) homogeneous assay using the isopeptide Ubiquitin-Lys-TAMRA substrate (either AUB-101...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
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