BDBM513602 (R)-3-(1,1-dioxido-5-(2-(trifluoromethyl)-1H-benzo[d]imidazol-5-yl)-1,2,5-thiadiazolidin-2-yl)pyrrolidine-1-carbonitrile::US11091488, Example 44

SMILES FC(F)(F)c1nc2ccc(cc2[nH]1)N1CCN([C@@H]2CCN(C2)C#N)S1(=O)=O

InChI Key InChIKey=ZVYFRXPIKFZSIS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 513602   

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM513602((R)-3-(1,1-dioxido-5-(2-(trifluoromethyl)-1H-benzo...)
Affinity DataIC50: 0.550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
Go to US Patent