BDBM513375 US11091472, Compound S-145

SMILES COc1ccc(cc1S(=O)(=O)NC1CCNCC1)-c1sc(N[C@H](C)CC2CCCCC2)nc1C

InChI Key InChIKey=OHDDRDFDRZREAI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 513375   

TargetPhosphatidylinositol 4-kinase alpha(Human)
University of California

US Patent
LigandPNGBDBM513375(US11091472, Compound S-145)
Affinity DataIC50: 5.50E+3nMAssay Description:In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
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TargetPhosphatidylinositol 4-kinase beta(Human)
University of California

US Patent
LigandPNGBDBM513375(US11091472, Compound S-145)
Affinity DataIC50: 1.00E+3nMAssay Description:In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
Go to US Patent

LigandPNGBDBM513375(US11091472, Compound S-145)
Affinity DataIC50: 2.00E+5nMAssay Description:In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
Go to US Patent

LigandPNGBDBM513375(US11091472, Compound S-145)
Affinity DataIC50: 2.00E+5nMAssay Description:In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
Go to US Patent