BDBM512318 US11084823, Example 19

SMILES C=CC(=O)Nc1cccc(Oc2nc(Nc3ccsc3)nn3cccc23)c1

InChI Key InChIKey=JQVTVFFVPGIZMA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 512318   

TargetTyrosine-protein kinase JAK3(Human)
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM512318(US11084823, Example 19)
Affinity DataIC50: 5.30nMAssay Description:Specifically, the inhibitory activities of JAK3 and BTK kinase were measured using a JAK3 kinase assay kit (Promega, V9441) and a BTK kinase assay ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM512318(US11084823, Example 19)
Affinity DataIC50: 62.9nMAssay Description:Specifically, the inhibitory activities of JAK3 and BTK kinase were measured using a JAK3 kinase assay kit (Promega, V9441) and a BTK kinase assay ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent