BDBM511752 2-(2-((2S,4R)-1-(2-(3-acetyl-5-(2- methylpyrimidin-5-yl)-1H-indazol-1- yl)acetyl)-4-fluoropyrrolidine-2- carboxamido)-6-bromopyridin-3-yl)acetic acid::US11084800, Cpd No. 62::US11708351, Compound 62

SMILES CC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2nc(Br)ccc2CC(O)=O)c2ccc(cc12)-c1cnc(C)nc1

InChI Key InChIKey=OQQAWNAQXSBJHU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511752   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM511752(US11084800, Cpd No. 62 | 2-(2-((2S,4R)-1-(2-(3-ace...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
Go to US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM511752(US11084800, Cpd No. 62 | 2-(2-((2S,4R)-1-(2-(3-ace...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent