BDBM511593 (R)-1-(3-cyanophenyl)-N((1-cyanopyrrolidin-3-yl)methyl)-1H-1,2,4-triazole-3-carboxamide::US11059809, Example 1

SMILES O=C(NC[C@H]1CCN(C1)C#N)c1ncn(n1)-c1cccc(c1)C#N

InChI Key InChIKey=SBEALMGULHSFTL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511593   

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM511593((R)-1-(3-cyanophenyl)-N((1-cyanopyrrolidin-3-yl)me...)
Affinity DataIC50: 10nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM511593((R)-1-(3-cyanophenyl)-N((1-cyanopyrrolidin-3-yl)me...)
Affinity DataIC50: 10nMAssay Description:Inhibition of USP30 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed