BDBM510057 N-{1-Cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl}-N2- [cyclohexyl(methoxy)acetyl]-4-methyl-L-leucinamide, DIAST-2 (9)::WO2021250648, Example 9

SMILES COC(C1CCCCC1)C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@H](C[C@@H]1CCNC1=O)C#N

InChI Key InChIKey=AGTLZKXDTWTAOI-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 510057   

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandPNGBDBM510057(WO2021250648, Example 9 | N-{1-Cyano-2-[(3S)-2-oxo...)
Affinity DataIC50: 254nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandPNGBDBM510057(WO2021250648, Example 9 | N-{1-Cyano-2-[(3S)-2-oxo...)
Affinity DataEC50:  970nMAssay Description:The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648