BDBM510050 N-{(1S)-1-Cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl}-4-methyl-N2-(pyrrolidin-1-ylacetyl)-L- leucinamide, trifluoroacetate salt (2)::US11351149, Example 2::WO2021250648, Example 2

SMILES CC(C)(C)C[C@H](NC(=O)CN1CCCC1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N

InChI Key InChIKey=PJWRDLQOAQQXBW-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 510050   

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandPNGBDBM510050(WO2021250648, Example 2 | N-{(1S)-1-Cyano-2-[(3S)-...)
Affinity DataIC50: 1.08E+3nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandPNGBDBM510050(WO2021250648, Example 2 | N-{(1S)-1-Cyano-2-[(3S)-...)
Affinity DataEC50:  7.52E+3nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1a(2019-nCoV)
Pfizer

US Patent
LigandPNGBDBM510050(WO2021250648, Example 2 | N-{(1S)-1-Cyano-2-[(3S)-...)
Affinity DataKi:  1.08E+3nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
Go to US Patent