BDBM50986 MLS000563434::SMR000232286::cid_160876

SMILES COc1cc2CC[n+]3cc4c5OCOc5ccc4cc3-c2cc1OC

InChI Key InChIKey=FPJQGFLUORYYPE-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50986   

TargetGlycoprotein 42(HHV-4)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50986(SMR000232286 | MLS000563434 | cid_160876)
Affinity DataIC50: 1.72E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetSUMO-conjugating enzyme UBC9(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50986(SMR000232286 | MLS000563434 | cid_160876)
Affinity DataIC50: 4.17E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetSUMO-activating enzyme subunit 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50986(SMR000232286 | MLS000563434 | cid_160876)
Affinity DataIC50: 8.68E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
TargetLysine-specific histone demethylase 1A(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50986(SMR000232286 | MLS000563434 | cid_160876)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21 using H3K4me2 peptide as substrate preincubated with enzyme for 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50986(SMR000232286 | MLS000563434 | cid_160876)
Affinity DataIC50: 140nMAssay Description:Inhibition of His tagged recombinant LSD1 (unknown origin) expressed in BL21 cells incubated for 10 mins followed by H3K4me2 peptide measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50986(SMR000232286 | MLS000563434 | cid_160876)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21 using H3K4me2 as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50986(SMR000232286 | MLS000563434 | cid_160876)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant KDM1A (unknown origin) expressed in Escherichia coli BL21 using H3K4Me2 peptide as substrate preincubated for 10 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50986(SMR000232286 | MLS000563434 | cid_160876)
Affinity DataIC50: 140nMAssay Description:Inhibition of LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 peptide as substrate incubated for 30 mins by Amplex Red re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed