BDBM5097 1,2,4-Oxadiazole Analogue 5f::4-[(2S)-2-acetamido-2-{[(1S)-1-(3-{[4-(trifluoromethyl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)ethyl]carbamoyl}ethyl]phenoxyphosphonic acid::CHEMBL103838

SMILES C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)c1nc(Cc2ccc(cc2)C(F)(F)F)no1

InChI Key InChIKey=KVCLASFFEYSLKL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 5097   

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5097(CHEMBL103838 | 4-[(2S)-2-acetamido-2-{[(1S)-1-(3-{...)
Affinity DataIC50: 7.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5097(CHEMBL103838 | 4-[(2S)-2-acetamido-2-{[(1S)-1-(3-{...)
Affinity DataIC50: 2.10E+5nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetGrowth factor receptor-bound protein 2(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5097(CHEMBL103838 | 4-[(2S)-2-acetamido-2-{[(1S)-1-(3-{...)
Affinity DataIC50: 5.00E+5nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5097(CHEMBL103838 | 4-[(2S)-2-acetamido-2-{[(1S)-1-(3-{...)
Affinity DataIC50: 7.20E+4nMAssay Description:Affinity for Src protein tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5097(CHEMBL103838 | 4-[(2S)-2-acetamido-2-{[(1S)-1-(3-{...)
Affinity DataIC50: 6.00E+3nMAssay Description:Affinity for Zeta-chain (TCR) associated protein kinase 70 kDa (ZAP70)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM5097(CHEMBL103838 | 4-[(2S)-2-acetamido-2-{[(1S)-1-(3-{...)
Affinity DataIC50: 5.00E+5nMAssay Description:Affinity for Syk protein tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed