BDBM5086 1,2,4-Oxadiazole Analogue 14a::4-[(2S)-2-(1-phenylacetamido)-2-{[(1S)-1-(3-{[4-(trifluoromethyl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)ethyl]carbamoyl}ethyl]phenoxyphosphonic acid

SMILES C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)Cc1ccccc1)c1nc(Cc2ccc(cc2)C(F)(F)F)no1

InChI Key InChIKey=WTOJROANXLUZGX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5086   

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5086(4-[(2S)-2-(1-phenylacetamido)-2-{[(1S)-1-(3-{[4-(t...)
Affinity DataIC50: 3.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5086(4-[(2S)-2-(1-phenylacetamido)-2-{[(1S)-1-(3-{[4-(t...)
Affinity DataIC50: 1.23E+5nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed