BDBM50745 3-(5,7-dimethoxy-2-oxidanylidene-4-phenyl-chromen-8-yl)-N,N-diethyl-3-(3,4,5-trimethoxyphenyl)propanamide::3-(5,7-dimethoxy-2-oxo-4-phenyl-1-benzopyran-8-yl)-N,N-diethyl-3-(3,4,5-trimethoxyphenyl)propanamide::3-(5,7-dimethoxy-2-oxo-4-phenylchromen-8-yl)-N,N-diethyl-3-(3,4,5-trimethoxyphenyl)propanamide::MLS000879482::N,N-diethyl-3-(2-keto-5,7-dimethoxy-4-phenyl-chromen-8-yl)-3-(3,4,5-trimethoxyphenyl)propionamide::SMR000465537::cid_16746297

SMILES CCN(CC)C(=O)CC(c1cc(OC)c(OC)c(OC)c1)c1c(OC)cc(OC)c2c(cc(=O)oc12)-c1ccccc1

InChI Key InChIKey=NSBWEIJFFUYGSD-UHFFFAOYSA-N

Data  2 KI  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50745   

TargetGlycoprotein 42(HHV-4)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50745(MLS000879482 | 3-(5,7-dimethoxy-2-oxidanylidene-4-...)
Affinity DataIC50: 5.40E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
LigandPNGBDBM50745(MLS000879482 | 3-(5,7-dimethoxy-2-oxidanylidene-4-...)
Affinity DataIC50: 5.26E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetG-protein coupled receptor 55(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50745(MLS000879482 | 3-(5,7-dimethoxy-2-oxidanylidene-4-...)
Affinity DataEC50:  1.31E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
TargetELAV-like protein 1(Human)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50745(MLS000879482 | 3-(5,7-dimethoxy-2-oxidanylidene-4-...)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of ELAV1 RRM1/RRM2 domains (unknown origin) interaction with ARE sequence of Mushashi1 transcript after 2 hrs by AlphaLISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetELAV-like protein 1(Human)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50745(MLS000879482 | 3-(5,7-dimethoxy-2-oxidanylidene-4-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of ELAV1 (unknown origin)-ARE sequence of Mushashi1 transcript complex formation after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetELAV-like protein 1(Human)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50745(MLS000879482 | 3-(5,7-dimethoxy-2-oxidanylidene-4-...)
Affinity DataKi:  590nMAssay Description:Inhibition of ELAV1 (unknown origin)-ARE sequence of Mushashi1 transcript complex formation after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetELAV-like protein 1(Human)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50745(MLS000879482 | 3-(5,7-dimethoxy-2-oxidanylidene-4-...)
Affinity DataKi:  5.10E+3nMAssay Description:Inhibition of ELAV1 RRM1/RRM2 domains (unknown origin) interaction with ARE sequence of Mushashi1 transcript after 2 hrs by AlphaLISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed