BDBM5066 1,2,4-Oxadiazole Analogue 5b::4-[(2S)-2-{[(1S)-1-{3-[(4-chlorophenyl)methyl]-1,2,4-oxadiazol-5-yl}ethyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid

SMILES C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)c1nc(Cc2ccc(Cl)cc2)no1

InChI Key InChIKey=ZPQPAIMZJIHQMX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5066   

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5066(4-[(2S)-2-{[(1S)-1-{3-[(4-chlorophenyl)methyl]-1,2...)
Affinity DataIC50: 1.40E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5066(4-[(2S)-2-{[(1S)-1-{3-[(4-chlorophenyl)methyl]-1,2...)
Affinity DataIC50: 6.60E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2005
Entry Details Article
PubMed