BDBM50633963 CHEMBL5417661

SMILES Cn1nccc1CNc1nc(N)nc2nc(ccc12)-c1cc[nH]n1

InChI Key InChIKey=MRKUOIJUAJQGNJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50633963   

LigandPNGBDBM50633963(CHEMBL5417661)
Affinity DataEC50:  8.30E+3nMAssay Description:Agonist activity at NLRP3 in human THP-1 cells assessed as LPS-stimulated IL-18 release incubated for 24 hrsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50633963(CHEMBL5417661)
Affinity DataEC50:  5.90E+3nMAssay Description:Agonist activity at NLRP3 in human THP-1 cells assessed as LPS-stimulated IL-1beta release incubated for 24 hrsMore data for this Ligand-Target Pair
In DepthDetails
PubMed