BDBM50633959 CHEMBL5411420

SMILES Nc1cc(NCCn2cccn2)c2ccccc2n1

InChI Key InChIKey=UPIKSDHRJMXJHG-UHFFFAOYSA-N

Data  2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50633959   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50633959(CHEMBL5411420)Copy SMILESCopy InChI

Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at NLRP3 in human THP-1 cells assessed as LPS-stimulated IL-18 release incubated for 24 hrsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/22/2024
Entry Details
Copy Entry DOIPubMed
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TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50633959(CHEMBL5411420)Copy SMILESCopy InChI

Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at NLRP3 in human THP-1 cells assessed as LPS-stimulated IL-1beta release incubated for 24 hrsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/22/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL