BDBM50633948 CHEMBL5401377

SMILES CCCOc1nc(N)nc2nc(ccc12)-c1cc[nH]n1

InChI Key InChIKey=BGBWTNOXSFPSEP-UHFFFAOYSA-N

Data  2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50633948   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50633948(CHEMBL5401377)Copy SMILESCopy InChI

Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at NLRP3 in human THP-1 cells assessed as LPS-stimulated IL-18 release incubated for 24 hrsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails
Copy BDB DOIPubMed
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TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50633948(CHEMBL5401377)Copy SMILESCopy InChI

Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at NLRP3 in human THP-1 cells assessed as LPS-stimulated IL-1beta release incubated for 24 hrsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails
Copy BDB DOIPubMed
Copy reaction URL