BDBM50633929 CHEMBL5393922

SMILES Cc1cc(\C=C(/C#N)c2nc3ccccc3[nH]2)c(C)n1-c1oc(C)c(C)c1C#N

InChI Key InChIKey=NAPUJOHOSNNFEY-UHFFFAOYSA-N

Data  4 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50633929   

TargetATP-dependent RNA helicase DHX33(Mus musculus)
Shenzhen Keye Life Technologies Co.

Curated by ChEMBL
LigandPNGBDBM50633929(CHEMBL5393922)
Affinity DataIC50: 520nMAssay Description:Inhibition of N-terminal/C-terminal 6x His-tagged wild type recombinant mouse DHX33 transformed in Escherichia coli BL21(DE3)pLysS cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetATP-dependent RNA helicase DHX33(Mus musculus)
Shenzhen Keye Life Technologies Co.

Curated by ChEMBL
LigandPNGBDBM50633929(CHEMBL5393922)
Affinity DataKd:  4.70E+3nMAssay Description:Binding affinity to N-terminal/C-terminal 6x His-tagged recombinant wild type mouse DHX33 transformed in Escherichia coli BL21(DE3)pLysS cells assess...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProbable ATP-dependent RNA helicase DDX59(Homo sapiens)
Shenzhen Keye Life Technologies Co.

Curated by ChEMBL
LigandPNGBDBM50633929(CHEMBL5393922)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of C-terminal 6xHis-tagged human recombinant DDX59 transformed in Escherichia coli BL21(DE3)pLysS cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPutative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32(Homo sapiens)
Shenzhen Keye Life Technologies Co.

Curated by ChEMBL
LigandPNGBDBM50633929(CHEMBL5393922)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of N-terminal thioredoxin-tagged human recombinant DHX32 transformed in Escherichia coli BL21(DE3)pLysS cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProbable ATP-dependent RNA helicase DDX6(Homo sapiens)
Shenzhen Keye Life Technologies Co.

Curated by ChEMBL
LigandPNGBDBM50633929(CHEMBL5393922)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of N-terminal thioredoxin-tagged human recombinant DDX6 transformed in Escherichia coli BL21(DE3)pLysS cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed