BDBM50632924 CHEMBL5395502

SMILES Cc1cnc(Nc2ccc(OCCCCCCC(=O)NO)c(F)c2)nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C

InChI Key InChIKey=XQYXAGOVMRYFIS-UHFFFAOYSA-N

Data  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50632924   

TargetHistone deacetylase 7(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632924(CHEMBL5395502)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632924(CHEMBL5395502)
Affinity DataIC50: 780nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632924(CHEMBL5395502)
Affinity DataIC50: 954nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632924(CHEMBL5395502)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632924(CHEMBL5395502)
Affinity DataIC50: 41nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632924(CHEMBL5395502)
Affinity DataIC50: 931nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632924(CHEMBL5395502)
Affinity DataIC50: 127nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632924(CHEMBL5395502)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632924(CHEMBL5395502)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632924(CHEMBL5395502)
Affinity DataIC50: 25nMAssay Description:Inhibition of JAK2 (unknown origin) incubated for 30 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632924(CHEMBL5395502)
Affinity DataIC50: 7nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632924(CHEMBL5395502)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632924(CHEMBL5395502)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632924(CHEMBL5395502)
Affinity DataIC50: 74nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632924(CHEMBL5395502)
Affinity DataIC50: 299nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632924(CHEMBL5395502)
Affinity DataIC50: 0.430nMAssay Description:Inhibition of HDAC1 in human HeLa cells nuclear extract incubated for 30 mins by multiplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632924(CHEMBL5395502)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of HDAC in human HeLa cells nuclear extract incubated for 30 mins by multiplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed