BDBM50632923 CHEMBL5433552

SMILES Cc1cnc(Nc2ccc(OCCCCCCC(=O)NO)cc2)nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C

InChI Key InChIKey=YJVWRVUQZNYKON-UHFFFAOYSA-N

Data  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50632923   

TargetHistone deacetylase 7(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632923(CHEMBL5433552)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632923(CHEMBL5433552)
Affinity DataIC50: 414nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632923(CHEMBL5433552)
Affinity DataIC50: 595nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632923(CHEMBL5433552)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632923(CHEMBL5433552)
Affinity DataIC50: 27nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632923(CHEMBL5433552)
Affinity DataIC50: 724nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPolyamine deacetylase HDAC10(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632923(CHEMBL5433552)
Affinity DataIC50: 116nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632923(CHEMBL5433552)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632923(CHEMBL5433552)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632923(CHEMBL5433552)
Affinity DataIC50: 22nMAssay Description:Inhibition of JAK2 (unknown origin) incubated for 30 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632923(CHEMBL5433552)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632923(CHEMBL5433552)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632923(CHEMBL5433552)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632923(CHEMBL5433552)
Affinity DataIC50: 59nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632923(CHEMBL5433552)
Affinity DataIC50: 303nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632923(CHEMBL5433552)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of HDAC1 in human HeLa cells nuclear extract incubated for 30 mins by multiplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632923(CHEMBL5433552)
Affinity DataIC50: 0.170nMAssay Description:Inhibition of HDAC in human HeLa cells nuclear extract incubated for 30 mins by multiplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed